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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b969c3878a159b79b4a9820ccda743e5594ea1784ae3bf6ad50c2e3e4f968ace' 
  AND token = '4r98w254i5vaHI/G1QWUnMMWrfSGWlP8XbBiwQLVkuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}