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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3de81e1a2223139af5aed3667e4fe5c9387c4194f1b57e475f90d0972c10aa' 
  AND token = 'qkAgbulR4OluN44efgX9Y3auZdvWJHHKRI7Hw624S1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}