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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef529e9e66a4c26f567d6c6b1138934973482bdeb1821e15aaf4815d3744a90' 
  AND token = '4OwzMo6yWIy1ZAAwmcgLUd02+QmzwWaQhPlamguuZhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}