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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce1f13133b29af4c1c75b9f316a027d04ce249193459e253ecccc2e5436bc47f' 
  AND token = 'GLo+/rm14Hc6D1OxByDo+pWfvA6h7Ii1pMB8O9mS9DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}