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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72eb5b4f1e87b4228398d70ba30efebccc8d2ba65e1ee1ab765fa25ef9df81bb' 
  AND token = 'hCLkNlVmHeK5/MUNAiSTkpa1kO39oP9LdwazxeGgvgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}