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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d6c32c4e99354613968bf1ca029ac24868ed002f7323687182722583deea49' 
  AND token = 'OPg9HUmsDxkJ4sxRo91D5qST+qvCK23StVPPYWY/100=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}