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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acbc7f76757eb4af06a142bcf86f77449b44882ecf4d3b16302f059facffef2a' 
  AND token = 'mG0ZOnlsqq2dXZb6rUN7dRAtlVESdzzvUDv8D0+qq6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}