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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb6a91404628710d95017e62e5a654e415a9a265e90d45dc8cf1882f8f0918b2' 
  AND token = 'CwMJEP2w/xP6mcySZHxInVBZ89MeeNFL4qwv69zLAds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}