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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0461aa641c963fa9a4fa56351f10c37ceb0cc14b1fe503885e7567d756d7cf' 
  AND token = 'ani6wPVUT1apc3rNY9esCPuNckfsjxnd/TlIcVJR5+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}