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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14313e8fc15fe4cfd72cb4be14c5da91c19fff7f545602b68efdcda4d9c621c9' 
  AND token = 'Jsuwn1oilh9ZqYEHJq+56psr6ZG8ajZ8roPD5LnjySY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}