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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5f4276c55545f05db326b398d8396849a11c9c5db2cc32ac7eb2e1bc1cb570a' 
  AND token = 'UQiIWAV0MXLPdP1m/pmV19Uu83BMXc5qTGDNlZCHDGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}