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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89dc9c52a87822f9745b142c435e213f97c1fdc1b4cfe5d072a909802e413d78' 
  AND token = 'ybhE8o2sAXbQH42XPIhKIY00h8LqvLZy7gNf9UZojfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}