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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff501b1fb1ed529aaa1448a44b0cdf515caeb3d0ec0dec22bc205dd580ddb42' 
  AND token = 'auiGaL24WxwJTQ0lkux54KI1InE/xp8HTpNL+YXzgFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}