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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4a61dfa5f8b034d355b3c215e9dbc02ff822b50e576b3e11e5bd38c90b5e85a' 
  AND token = 'yTqQ/YtmlAVkUM4U24DXpd6tsLALXMrzSgNtLQ3vsJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}