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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae67d6801c7726633644192a53942d3472787f8498f4260a5b110bc48ce0b762' 
  AND token = 'FuuBDLl6jFuo/HE7pcu1GlRtDxWOna5CfkFy+scyKDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}