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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28fcf2b946699e01cc13a34ffa655583b4c4f6bf3046fd605eebe13db16650b4' 
  AND token = 'O1vvYQ8mRBahoPSWUAsyKt3Ll5gtDD/Ym1qBP43f3Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}