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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1140701b419a1cd3bc05b14a24e1f08a5c0f0581945a6da65857fbdf60b50b07' 
  AND token = 'Oq33ayTA3eUi8zXxU1ot0vXUSEGdqcXu4Aq7vHUeGng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}