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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d27465370ddda754cd4e792ebc0c0072c82247e1d233f4563a321927a49914d' 
  AND token = '+b30XjfM9wkiO5SM9sFYWF8IffI256OpKdLI6fVllSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}