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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1d46730ff5532503ccf3bc62b6f90afbb34be53b6eb340177b914615626bd5' 
  AND token = 'ErjJuthfJmQIzv9anK2QEuK6FbCzdThtJ4tOjWLtN6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}