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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a323857f717088cc155006314ff54a09a2f5e7b34160fe3ac3b42f10332d772' 
  AND token = 's++gmRUZTUmq9SjwnRrO/9MwJ0wuU0EWISMdpH01o5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}