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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a679d2809aaf49c780f9018c7b32dab27221a526f0a0d495ea8765b4a69a8ae8' 
  AND token = 'T9aTASH2J6iAEgDRnIu1zqDjeq3kz3Y9t7HoAdiRf0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}