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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e2184fab70fc7ec9cc59bbdfd1a573fc8c420aec0b822fa294a9f7da8b23cb' 
  AND token = '+1NTmCeWG6svMAI8qjj1pKnlcJz+LotvMpF3wP+nu8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}