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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97901688111be25381e9fcf11fbfcda87230d985bfd412c06b0eed69cdb39b18' 
  AND token = 'eneMsDP1RKQBCII3RByhZbsqibIVwoGKG2B45mTwLzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}