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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1446dc849412d498e3b05c3262ac464a287cedf57728772400d092ef5ba7669b' 
  AND token = 'Iq9e9/p/6hzdCnkOiO25nJehF0T0MtWoLRdMC1NgW3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}