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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '559d6d205727a9f0b6ff9d7ecc554c7ec0cbc319d04aacb067040ff77eb9f255' 
  AND token = 'rWoP3YUE8hTIiXJLDh4FI5FARiFk8AB9SWJ4GoIwogw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}