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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63443e966765d95721f855f55749e0284387004af0030029e868e5e37e237516' 
  AND token = 'mGpDp3B/0+3AUWsn6Y1NGvfGrNXVIZ420LPqSnJ9LB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}