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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6dcc935437e4ce2a45d54f3364d6676a1b209f9ef8f0d44237a915c66770eb6' 
  AND token = 'GyrJk/FOTlM9KT8e7PBBO6d5SmIPjN1q0zmKZnXJpK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}