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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be54b8ea008cf280e4d5d059ac71957727a2225802a9b52cfdb667c9a3a68f2f' 
  AND token = 'oqINAH/rnxhh7x9R8k/C1Ve/cXZRnQaKdJTz1ktKV18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}