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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e79eda09ab4e693ad313351aaec0163928c4d41d1c165b6856a394d1108c532' 
  AND token = '+/JyS3zeWicZrKeYCa5VSJA9+C5VKQZElDasBB5RTRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}