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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7351fd3019208cea632dea3dc208571952738c2b50e01a505d7a0f8a2a6ab916' 
  AND token = 'la9y86XYZc1BEcAeCJN63PTt2RbIAYCaoGEC0lActrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}