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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f53b427610549605e0b84c89501f262f0e6743537d44cc817591eab0354d7c7' 
  AND token = 'KyypzbJw27sLE3bRd5R76qcjZfYKkuxQIZbZ6P69V4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}