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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86b41d6c6fad3cc03fc0b93acca5dc2d76995142e92ccd37e6b0f7c1fbc31046' 
  AND token = 'hk2cJqm8kjebPt4hesKRmrJmOTVVqDt/dsiMP1zM+ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}