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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a41f77814c4a4e70eae2439ffbf0ac6b37fe4c3bba076ff04e25633983a34ca' 
  AND token = '/R7Cs/nECrW4MZ2tlRvcVKPxOh4j40c3hx+ODNdlqDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}