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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e95fe73ffce3b9c1a62692c3f9f5a6d1a993274799ea01bde93c84c409da46' 
  AND token = 'nwWg5fbW0Wr8sz59kzudyp/4njWUzQ+ZTX+tFGrXfCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}