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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd002720cc0b651ae1e7f4f8f18fb4a23d388f825ea3d06e488f8e89622a0bbe' 
  AND token = 'Kz9/e1wbqJ4SXcK6tj4PkTuVNHthQHk4UuciB+3YJiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}