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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5aa86578c631a4562670034a161b9d0c520238c159dc3efbcd545d63467dfe3' 
  AND token = 'vb3ctwijMod9tpcA6D/v5nrdh9G9mysqj0ZE/ElbN3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}