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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff827ec67c8f4eba41066cc9ab9d80dc7846b3644a4ea9d598ad2845d82f4f9' 
  AND token = 'FC4uA9xw7uLqZ9tB5idwMlF4cKZxHJwSsHkgsJZZUaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}