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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '176018c0bd125498b2cf482b639dfad856d720aa0bd1f79975f89b4126816fa3' 
  AND token = 'UOf2wEw/m0Vk/N42+lkgs9w4HkcuJGxItY7KtJnINx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}