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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1246e64dcdac3f80521f472c220bc83b2670960f95e1e3b9b4558c7d874ca9' 
  AND token = 'YyuJIgc99bAvnyMTreXKiE2JnWC4BkPxMJVa6vLbA2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}