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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04562938f493b18aabb94b6cc2cc42697ca52c187569217ddb51828ef4fb18f5' 
  AND token = 'FaNTdm1+sQGMmMtoDrSGGSHRrGEpt109ELmLsIvzgXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}