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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa7406c743472495f0778b80c6e11190ea9220b0fb00c15df1baf8961d199f0' 
  AND token = '2i78gtsPbau43yQN0l+cpmsuQ3UdIPN+M3nygIIwR8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}