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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d3f6e249e1c0580e4e9b615f6e2a4c272eea5fe464787a9706c07a1c961ab0' 
  AND token = '3nAHzNUYUnyBrV5f9rfwsvDi1SNyYk19MfvGvKaWIHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}