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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c1f494c5057c49461ac8bee0c65be9e60ca82eca536e9d8a12d8b23226ab556' 
  AND token = 'lPCIiQYD34xp/o1AZnIxgRg+2urEnB+ZpOJl426uYhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}