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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12507e59ff805f541e0cd44efd1d7c71aa5ccb75d91dc0f1600167da1dcd755e' 
  AND token = 'h6RyJSSwYUmdXywFW2186bqp9odG2OGHVE9Q90WUyKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}