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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2101285e488bb64132c77466278846c3acc47d57a39e919918f35e87c005c4ac' 
  AND token = 'DO4XA7OwHnvF01ruVbk0/e4nuljmAz+IM+4DfGTNrIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}