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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2685dba68a43de635fb28dfa412fb8e4aa06866b6f33e77486f5545e99f3b94b' 
  AND token = 'DYkQcxhMiz1pyMBEk/qraAiNVl6Kdmi/dHYMalpdvbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}