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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0bc81fba6c7f5ca03a5bc11ff6185b83c1d4c7bf9343773f0c109089373f3f' 
  AND token = '/OoVIT93tYflew6dg+NtxKrUVq0WECAc9TknFwqLoKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}