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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f37517c38ecf1a1ee2c47e93aa9d2cca85acc1e7e20daaf937caa32d6e2635de' 
  AND token = 'tf/MyFqPO6hGWC42/wIMnGNLLTEPmL2VCr65KCrbt8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}