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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15de76eb5ef66f62dac1a4ec885daed4f4828d3dcc48624375975d956734759a' 
  AND token = 'O2V7RP4vRJHpuhpN+d7VrwA8IZZIAdTlkilVbsl3SP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}