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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eea5001b0d5ba21c20d8d01b82e2c1cf3563367cef171db13ce6580e3dabb3bc' 
  AND token = '8dPM6d5gRQ6wuaVcL5xsKCHoCU+NwPhRgWLP+OqljVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}